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Antidepressants and antipsychotics might block the effect of LSD by acting on the same receptors and outcompeting its capacity to bind. Antidepressants mirtazapine and trazodone act around the five-HT2A and five-HT2C receptors wherever they block serotonin and various molecules from binding.Health care Disclaimer: DrugRehab.com aims to Increase the